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Bio-IT World Weekly Update 
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A Bio-IT World publication 
alt  Tuesday, January 12, 2010  alt  |  Bio-ITWorld.com  |  Archives  |  Advertising  |  Your Account  |  CHI Conferences  |    Subscribe  | 
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Industry Trends 

An Analysis of Worldwide Prescription and OTC Sales by Technology
(2002 - 2012)
 

By Mark P. Mathieu 

EvaluatePharma® calculates that worldwide pharmaceutical sales from biotechnology products increased 20%, to $94bn, in 2007.
Read more 

 

Latest eNewsletters

eCliniqua  
New Privacy Concerns with
'HIPAA 2'
Jan 4, 2010 


Pharma Services  
News
 
 
BioSeek-Asterand Deal is Rich with Synergy
Dec 9, 2009 

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Sales Contacts
For advertising information contact: 

Alan El Faye 
VP, Advertising Sales - Western US, Canada, Europe, Pacific Rim
213-300-3886 
 

Kay O. Christopher 
Regional Sales Manager, Advertising Sales - Eastern US, Midwest and India
860-693-2991
 

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Link to Us! 
You are welcome to link to articles on our website. Contact Allison Proffitt for details.

e-Prints & Reprints 
To post a full article from  Weekly Update  or Bio-IT World on your website (not just a link), or for paper reprints, please contact:
Ashley Zander 

The YGS Group
717-505-9701 ext.125
 

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IN THIS ISSUE 
alt  New CMS Method Pinpoints Positive Selection Signatures in Human Populations 
alt  Diagnosing Bilski 
alt  Zinc Finger Techniques Could Be Gene Therapy Breakthrough 
 
  
Organize, Analyze and Visualize Chemical and Biological Data 

Scientists involved in drug and molecular discovery projects can spend hours each week dealing with mountains of data to determine which are the most promising compounds for further studies and review.  Now there is a way to shorten that cycle, regardless of the data source, format, or amount of information collected.  Click to learn more 

 
THIS WEEK IN BIO-IT 
 

New CMS Method Pinpoints Positive Selection Signatures in Human Populations
By Kevin Davies 

In a new paper published online this week in Science, Harvard's Pardis Sabeti and colleagues describe a powerful computational strategy for pinpointing precise signatures of positive selection in human populations. Applying this "Composite of Multiple Signals," Sabeti's team refined genome regions under selection, identifying dozens of genes that have shaped human population genetics. Read more. 

 

EXPERT COMMENTARY 
Diagnosing Bilski
By Brian Dorn 

The U.S. Federal Circuit's In re Bilski decision provides a framework on patentable subject matter. Although the claims in Bilski are methods of hedging risk in commodities trading, these holdings have and will be applied to all technologies, including biotech process claims, and the U.S. Supreme Court has agreed to review Bilski, and a decision should issue this Spring that could greatly affect the diagnostic industry. Read more. 

 
 

Last Week's Most-Read Story
AstraZeneca Saves $150m with Better Data Management 

  
Take Control of your Scientific Data 
Struggling to access, aggregate and mine scientific data across your organization? Traditional business intelligence (BI) technologies cannot handle advanced scientific data processing and analysis. Learn how Accelrys' scientifically-relevant BI solutions can meet the needs of your scientific and clinical research community.
Download the whitepaper .
 
 
ELSEWHERE IN THE PRESS 
 

Zinc Finger Techniques Could Be Gene Therapy Breakthrough
Scientists at the University of Pennsylvania have used a new technique to to disrupt a gene in T cells. The results are in clincal trials now and if the technique worked, the altered T cells could render the patient immune to AIDS. New York Times 

 
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PODCASTS 

How New Molecular Modeling Software is Dramatically Improving Workflows 
Sponsored by Tripos

Advanced molecular modeling software now has the ability to make routine tasks faster and easier for life scientists, and researchers. Significant benefits include the enhancement of key discovery workflows from obtaining data to delivering findings.  In this brief podcast, learn about:
 

  • New avenues for science being opened up through exciting; new software advancements 
  • Strategy and applications driving computer-aided design that are increasing scientific productivity and efficiency 

Download now 



Technology Challenges and Outlook for Drug Safety Management in Clinical Trials
 
Sponsored by Medidata 

This podcast will discuss the drug safety regulation challenges that the biopharmaceutical industry is facing in clinical trials and the emerging new technologies that can help researchers to address them.
 
Industry experts and executives from Medidata will address the following questions: 

  • What are the challenges associated with drug safety in clinical trials? 
  • How can a clinical study sponsor be better prepared for regulatory agency safety inspections? 
  • What is the outlook of technology in safety data management? 

Download now 

To have your podcast featured here, contact Lynn Cloonan for more information. 

 

SPONSORED LINKS 


To have your product or service featured here, contact Lynn Cloonan  for more information. 
 

Insight Pharma Reports 

Immunotherapies and Vaccines for Nontraditional Indications
Author: Lucy J. Sannes, PhD, MBA 

Immunotherapies and Vaccines for Nontraditional Indications Applications of immunotherapies and vaccines for prevention and treatment of infectious diseases and cancer are well known.  Immunotherapies being developed or used for treatment of other diseases (i.e., beyond prevention and treatment of infectious diseases and cancer) are the focus of this report. These may work by different mechanisms of action, and available information regarding how these immunotherapies work is presented.
Read more.
 

 

FEATURED EVENTS

To have your event featured here, contact Lynn Cloonan for more information.

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BEST PRACTICES 2010 

Bio-IT World's 2010 Best Practices Awards Program

Entry forms are now available for Bio-IT World's 2010 Best Practices Awards program. The program is intended to spotlight companies whose use of innovative technologies is making a positive difference in biomedical R&D and drug discovery and development. 

Bio-IT World is also making available a free compendium of Best Practice entries from 2009 to help ensure the lessons learned are widely spread. The compendium can be downloaded here . 

Full details of the entry process and the entry form are available by clicking here . The deadline is January 18, 2010. 

2009 Best Practice Categories:
*Basic Research & Biological Research
*Drug Discovery & Development
*Clinical Trials & Research
*Translational Medicine
*Personalized Medicine
*IT & Informatics
*Knowledge Management
*Health-IT
*Manufacturing & Bioprocessing
 

If you have questions, write to  aproffitt@healthtech.com 

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FEATURED CONTENT 

The Key to Life Sciences Data alt Management: Transparent Migration Life sciences organizations face new data management challenges as the volume of research data grows and more data is kept online for longer times.  Download Whitepaper (Sponsored by: BlueArc)


Protect Your Scientific Intellectual alt Property: Proof of Lab Informatics Data Authenticity is Your Best Legal Defense
As a bio-technology or life sciences organization, your formulas, treatments and research and discoveries are the "lifeblood" of your business. But if you aren't protecting the integrity of your scientific data in your lab informatics systems, you risk losing IP ownership, revenue and consequently your business if you can't prove time-of-creation and data authenticity. Learn how you can implement simple, cost-effective and automated controls to protect your scientific intellectual property. Download Whitepaper (Sponsored by: Surety, LLC)



The Promise of Imaging Biomarkers 
alt Imaging biomarkers are poised to join biochemical and molecular markers as drivers of drug development and disease management. They enable researchers and clinicians to see into the body without invasive procedures. They frequently provide earlier detection of disease and its progression than molecular markers. Researchers use them to see in detail how their candidate drugs behave such as determining the percentage of target receptors occupied by a drug or observing a drug's ability to cross the blood/brain barrier. They promise to save time and money too.
Download this white paper . (Sponsored by: Thomson Reuters ) 

Beyond EDC…Optimizing ROI by alt Streamlining Clinical Research Processes
Although EDC brings tremendous efficiencies to clinical data collection, numerous repetitive clinical development activities exist beyond its scope which are in need of more efficient processes.  As these activities move from paper-based to electronic, the transition can be eased through the use of intelligent PDF forms.  Using XML capabilities, intelligent forms can follow workflows while leveraging established point solutions such as EDC, CTMS and IV/IWRS to optimize return on investment.
 Download Whitepaper (Sponsored by: Adobe) 

To have your white paper featured here, contact Lynn Cloonan for more information. 

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EXCLUSIVE WEBCAST 

Life Science Webcasts from Bio-IT World and Cambridge Healthtech Media Group
Life Science Webcasts 

New 
Moore's Law and the Future of Genome Sequencing
Guest: Jonathan Rothberg, Ph.D., Founder/CEO Ion Torrent Systems; Founder Curagen, 454 Life Sciences, Rain Dance
Editorial inteview conducted by Kevin Davies, Ph.D., Editor-in-Chief of Bio-IT World with Jonathan Rothberg reflecting on the past decade of his accomplishments and a glimpse at his new project, Ion Torrent Systems.  Interview conducted at CHI's Exploring Next Generation Sequencing conference in September 2009. 
 
Download Now 


New 
Oxford Nanopore's Third-Generation Sequencing Technology
Guest: John Milton, Ph.D., Vice President Research, Oxford Nanopore Technologies UK
Editorial interview conducted by Kevin Davies, Ph.D., Editor-in-Chief of Bio-IT World with John Milton that offers insights into Oxford Nanopore's potentially revolutionary new sequencing technology, which marries exonuclease cleavage of DNA and protein nanopores.  Interview conducted at CHI's Exploring Next Generation Sequencing conference in September 2009.
  Download Now

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Contact the Editor 
We invite your comments and feedback for this edition of Weekly Update. 

Managing Editor
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alt Published by Cambridge Healthtech Media Group , division of CHI , Copyright Â© 2009; All rights reserved.  Bio-IT World Weekly Update may not be reproduced, electronically or in print, by any means, mechanical or electronic, in whole or in part, without written permission of Cambridge Healthtech Media Group, 250 First Ave., Suite 300, Needham, MA, 02494. 
For reprints and/or copyright permission, please contact The YGS Group, 3650 West Market Street, York, PA 17404. Phone: 717-825-2150, ext. 125. Email:  ashley.zander@theYGSgroup.com